Abstract : The aim of this study was to determine the incidence of bacterial infections in patients hospitalised in the burns unit of Constantine University Hospital, and to establish their bacteriological profiles. Also, to assess the antibiotic resistance of the strains isolated. The study involved 160 patients admitted to the burns unit of Constantine University Hospital. According to the data collected from inpatient records, 87 patients were found to have an infection, representing 54.37% of patients. During 2018, 151 positive samples were taken, 49% from blood cultures, 29% from probes and 11% from CBEUs. However, mycological examinations accounted for only 7%, catheters 3% and pus 1%. The bacteria most responsible for infections in hospitalised burn patients are coagulase-negative Staphylococcus at 21%, followed by Acinetobacter baumanii (19%), Pseudomonas aeruginosa (15%), klebsiella pneumoniae (9%) and Proteus mirabilis (6%). Several bacteria appeared resistant to antibiotics, including Acinetobacter baumani, resistant to Gentamycin 27% and Ticarcillin 27%; Pseudomonas aeruginosa to the majority of antibiotics (Ticarcillin 35%, Gentamycin 34%). Coagulase-negative Staphylococcus showed significant resistance to Penicillin and Oxacillin. Among Enterobacteriaceae, resistance to ticarcillin and amoxicillin was observed.